Neurowave is an innovative platform focused on the syndrome of Coma, Vegetative Status and Staus of Minimal Consciousness. This unique technology allows to administer multisensory stimuli and, at the same time, to acquire the neuro-biophysiological parameters of patients in a vegetative state and state of minimum consciousness, automatically highlighting the eventual correlation signals, allowing the clinicians to investigate the study of a pathology that to date is still largely unexplored and at the same time it represents an area with a high social and emotional impact. The analyzes and the protocols that can be implemented by the system include VEP evoked potentials by flash and pattern; Potentials event-related (P300, MMN, N400, P600...), with the possibility of review of the single times EEG spectral reactivity by structured and non-structured stimulation EEG reactivity to Bright Intermittent Stimulation (BIS) EEG data clustering, to verify the presence/absence of more stages in the EEG recording and their characteristics Wide signal cleaning functionalities set for the EEG signal artifacts (Independent Component Analysis, Regression from EOG) Reactivity of Heart Rate Variability to the emotive stimuli